REFRESHER

REFRESHER 1 – Translational science

Created by: Henri Leuvenink, Groningen, The Netherlands; Gavin Pettigrew, Cambridge, United Kingdom

Outline | The wonders of basic research: the clinical needs translational research the fastest and most efficient way from one to another.

Key Learnings

  • Clinical models on warm perfusion and organ manipulation
  • Pre-clinical modelling of the allo immune response: is it relevant?
  • Why bother about pre-clinical models?

 

REFRESHER 2 – Learning from neighbouring specialities

Created by: Menna Clatworthy, Cambridge, United Kingdom; Luuk Hilbrands, Nijmegen, The Netherlands

Outline | The pipeline of new immunosuppressive drugs is rather dry. Nevertheless in cancer / hematological malignancies and autoimmunity new drugs are introduced that may also find application in transplantation. A brand new field is immunometabolism.

Key Learnings

  • Stealing from cancer
  • Learning from autoimmunity
  • Lessons from immunometabolism

 

REFRESHER 3 – Big data

Created by: Soren Sorensen Schwartz, Copenhagen, Denmark; Thomas Resch, Innsbruck, Austria

Outline | For health care professionals it is important to understand the possibilities and pitfalls in big data analysis in order to be able to direct this research area towards clinically relevant areas. In order to interact with professionals within big data analysis, i.e. within bioinformatics and related area of statistics, we need to have a more profound understanding of big data analysis than just looking at it as black box. We need to understand the various steps in big data analysis i.e data curation, data analysis modalities, data interpretation etc.

 

REFRESHER 4 – inflammation

Created by: Soren Sorensen Schwartz, Copenhagen, Denmark

Outline | Inflammation, frailty and morbidity in relation to organ transplantation – how to evaluate and what is the connection. Inflammation and antibody mediated rejection – the missing link? HLA and inflammation – what is the connection and is there a clinical relevance. Anti- inflammatory and cardiovascular risk reduction – what are the treatment options.

Key Learnings

  • Inflammation, frailty and morbidity in relation to organ transplantation. How to evaluate and what is the connection?
  • Inflammation in relation to rejection – the missing link?
  • Anti-inflammatory treatment in cardiovascular risk reduction –  from bench to bedside.

 

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