PLENARY 1 – Be inspired, Be driven

Created by: Finn Gustafsson, Copenhagen, Denmark; Allan Rasmussen, Copenhagen, Denmark

Outline  | Be innovative. Be driven. Be inspired. Be Bold. Inspiration and Progress: a common denominator for Art, Business and Science


PLENARY 2 – Single Cells Omics Generating an atlas to chart transplant organs

Created by: Menna Clatworthy, Cambridge, United Kingdom; Gavin Pettigrew, Cambridge, United Kingdom

Outline  | We currently use ‘omics’ technologies (proteomics, transcriptomics, genomics), in transplantation to identify biomarkers, signatures, or genetic variants associated with differential outcomes. These technologies have been applied to bulk tissue or blood samples. Recent advances in genomics and informatics allow their application at the level of a single cell, using RNA sequencing and mass cytometry. These approaches are revolutionising our understanding of the cellular composition, origin and interactions within human organs and are being used to generate the first draft of the Human Cell Atlas (HCA) – an ambitious international effort. The HCA will catalogue every cell and every cell state in the human body to deliver health-transforming insights into human biology. For example, single cell RNA sequencing has already allowed researchers to identify a previously unknown type of dendritic cell in peripheral blood.


PLENARY 3 – Perfect Organ Preservation and reconditioning – an elusive dream?

Created by: Ina Jochmans, Leuven, Belgium; Henri Leuvenink, Groningen, The Netherlands

Outline  | Perfect organ preservation – a cornerstone of transplantation – might sound like a dream … yet, the last years have seen tremendous progress. Technology has caught up with our creative minds and we are now able to preserve organs in dynamic and more physiological conditions than static cold storage ever could. Organ perfusion is here to stay, paving the path towards perfect organ preservation and opening doors to organ reconditioning, treatment, modification, management and more. Be inspired and motivated by the most creative thinkers in the organ preservation arena and discover what they dream of.

Key Learnings

  • Focus on liver perfusion
  • Focus on normothermic regional perfusion
  • Focus on how machine perfusion strategies might influence immune regulation in ischemia-reperfusion injury
  • Focus on heart and lung perfusion


PLENARY 4 & PRESIDENTIAL SESSION – Dealing with organ failure: a change in the direction of travel?

Created by: Erik Berglund, Stockholm, Sweden; Vassilios Papalois, London, United Kingdom; Lorenzo Piemonti, Milan, Italy; Thomas Resch, Innsbruck, Austria; Andreas Zuckermann, Vienna, Austria

Outline  | The session aims to critically appraise all the indications in modern practice that we are moving into a more holistic approach when dealing with end stage organ failure including modalities beyond transplantation.

Key Learnings

  • Clear signals FROM ESOT2019 Congress in Copenaghen that the direction of travel is changing
  • Clear signals BEYOND ESOT2019 Congress in Copenaghen that the direction of travel is changing
  • How our practice for treating organ failure will look like at the ESOT Congress of 2039?